siporem siporem

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Siporem

Prospect

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Patient Information

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Formula

Each capsule contains: Siponimod 0,25 mg o 2 mg.
This medication is gluten-free..

Mechanism of Action

Selective Immunosuppressor. ATC code: L04AE03.

Indications

Siporem (Siponimod 0,25 mg y 2 mg) is indicated for the treatment of adult patients with relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting multiple sclerosis (RRMS), and active secondary progressive multiple sclerosis (SPMS)..

Posology

The recommended maintenance dose is 2 mg once daily (1 mg in patients with CYP2C9*2*3 or *1*3 genotypes). A 5-day stepwise titration regimen is required: Days 1-2: 0.25 mg once daily; Day 3: 0.5 mg; Day 4: 0.75 mg; Day 5: 1.25 mg; Day 6 and thereafter: maintenance dose.

Package Size

Treatment starter pack:
SIPOREM 0.25 mg: Each pack contains 12 film-coated tablets.
Treatment maintenance pack:
SIPOREM 2 mg: Each pack contains 28 film-coated tablets.
SIPOREM 0.25 mg: Each pack contains 120 film-coated tablets.

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